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KMID : 1025520120540040241
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Journal of Animal Science and Technology
2012 Volume.54 No. 4 p.241 ~ p.246
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Phylogenetic Analysis of Korean Native Goats Based on the Mitochondrial Cytochrome b Gene
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Kim Jae-Hwan
Byun Mi-Jeong
Ko Yeoung-Gyu
Kim Sung-Woo
Kim Sang-Woo
Do Yoon-Jung
Kim Myung-Jick
Yoon Sei-Hyung
Choi Seong-Bok
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Abstract
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The goal of this study was to verify the phylogenetic status of the Korean native goats (KNG). We determined the complete sequence of the mitochondrial cytochrome b gene in 48 goats among four populations. We also analyzed genetic variability within goats, and a phylogenetic analysis was performed by comparison with other country's goats. Three nucleotide substitutions were detected, and two of these were missense mutations that occurred due to a substitution of amino acid. Four haplotypes were defined from KNG. Three of these haplotypes were only found in the Chinese goat. However, the other haplotype was KNG-specific. In the phylogenetic analysis, four clades (A~D) were classified among domestic goats, and the KNG was classified into clade 1 that estimated as lineage A based on the D-loop sequence. Each haplotype from the KNG was clustered closely with that of the Chinese goat. The results of haplotype distribution and phylogenetic location suggest that strong gene flow occurred from China to the Korean Peninsula.
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KEYWORD
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Korean native goat, Phylogenetic analysis, Cytochrome b, Haplotype, Gene flow
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